The relic density obtained in Freeze Out of Non-Relativistic Species implies that in order to reproduce the correct relic abundance, dark matter particles must have an annihilation cross-section of the order .
We can consider a simple case where the DM particles self-annihilate into SM particles through the exchange of a gauge boson (like in s-channel). Then, the annihilation cross-section is of the order , where and the correct relic density is obtained for masses of the order of GeV.