(insert diagram) This process is actually a rotated version of the Electron-Muon scattering. Hence, we will exploit the Crossing Symmetry which relies on the Lorentz Invariance of the Amplitude. We need to cross the initial state muon into the final state and the final state electron into its initial state, i.e., k2 → -k2 and p1 → -p1. Thus, Mandelstam variables change to s=(k_1+k_2)^2 \;\;\;\;\;\;\;\;\longrightarrow\;\;\;\;\;\;\;\;(k_1-k_2)^2=t$$$$t=(k_1-p_1)^2 \;\;\;\;\;\;\;\;\longrightarrow\;\;\;\;\;\;\;\;(k_1+p_1)^2=s$$$$u=(k_1-p_2)^2 \;\;\;\;\;\;\;\;\longrightarrow\;\;\;\;\;\;\;\;(k_1-p_2)^2=u Thus, The crossing relation has turned at-channel process into ans-channel process. We need to careful to not apply these crossing relations to the flux factor. It has to be recomputed from the new initial states. Hence, In a collider environment with The annihilationcross-section is then Now, the total annihilation cross section is, \text{(Using }d\Omega=d\phi dcos\theta)$$$$\sigma=\int_0^{2\pi}d\phi\int_{-1}^1dcos\theta\frac{e^4}{64\pi^2s}(1+cos^2\theta)$$$$=\frac{e^4}{32\pi s}\frac{8}{3}=\frac{4\pi\alpha^2}{3s}\;\;\;\;\;\;\;\;\;\;\;\;\;\text{with }\alpha=\frac{e^2}{4\pi} where α is the fine-structure constant.